Premenstrual Dysphoric Disorder (PMDD) is a chronic and cyclical, reproductive mood disorder. Symptoms of PMDD present 7-14 days before menstruation during the premenstrual or luteal phase of the cycle and usually improve once the menstruation starts. The condition affects up to an estimated 8% of reproductive aged women1. While PMDD isn’t caused by hormone imbalances, many people with PMDD also have hormonal issues.